What brain region is thought to be underactive in individuals with bipolar disorder?

The left temporal lobe has been associated with various cognitive functions, including language processing and emotional regulation. In individuals with bipolar disorder, neuroimaging studies suggest that there may be hypoactivity in this region, which could contribute to the mood instability and cognitive impairments often observed in the disorder. This underactivity may affect the individual's ability to process emotions or regulate mood effectively, leading to the extreme mood swings characteristic of bipolar disorder.

Furthermore, while other brain regions also play critical roles in mood regulation and may show changes in activity levels, the specific reference to the left temporal lobe highlights its importance in the context of bipolar disorder and underscores its potential involvement in the emotional and cognitive symptoms associated with the condition.